가토의 두개골 골결손부에 탈단백 우골 이식시 혈소판 농축 혈장과 피브린 실란트의 효과
THE EFFECT OF PRP AND FIBRIN SEALANT WITH THE DEPROTENIZED BOVINE BONE IN THE RABBIT CRANIUM
이용인, 신승윤, 이동환, 홍종락,
소속 상세정보
이용인 ( Lee Yong-In ) - 성균관대학교 의과대학 삼성서울병원 구강악안면외과
신승윤 ( Shin Seung-Yun ) - 성균관대학교 의과대학 삼성서울병원 치주과
이동환 ( Lee Dong-Hwan ) - 성균관대학교 의과대학 삼성서울병원 보철과
홍종락 ( Hong Jong-Rak ) - 성균관대학교 의과대학 삼성서울병원 구강악안면외과
KMID : 0355620070330030221
Abstract
Purpose: The purpose of this study is to evaluation of effect on bone formation of PRP and fibrin sealant with deproteinized bovine bone(Bio-Oss) grafts on rabbit cranial defect.
Material and Methods: Twelve rabbits were used as experimental animal Two equal 9㎜ diameter cranial bone defects were created in each rabbit and immediately grafted with Bio-Oss only, Bio-Oss and PRP, and Bio-Oss and Fibrin sealant. Rabbits were sacrificed at 4 and 8 week. The defects were evaluated by histomorphometric analysis.
Results: Kruskal-Wallis tests were performed comparing new bone formation via histomorphometric analysis. No statistically significant difference of new bone formation was found between Bio-Oss only, Bio-Oss and PRP, and Bio-Oss and fibrin sealant at 4 and 8 weeks (P＞0.05).
Conclusion: This study fails to find a stimulatory effect of PRP and Fibrin sealant on New bone formation of Bio-Oss grafts by histomorphometric analyses.
키워드
Bio-Oss;PRP;Fibrin sealant;Deprotenized bovine bone
원문 및 링크아웃 정보
등재저널 정보